Exosomes have become one of the biggest buzzwords in skincare, but behind ( plated )™ Skin Science, they represent an actual scientific breakthrough rather than a trend. Developed by physician-scientists from the Mayo Clinic Van Cleve Cardiac Regenerative Medicine Program after more than 20 years of research, ( plated )™ uses platelet-derived exosomes to help visibly renew the look of skin and hair, backed by 10+ peer-reviewed clinical studies.

What Are Exosomes, Really?

Exosomes are nano-sized vesicles that your body produces naturally — there are roughly 35 quintillion of them at work in your system right now. Discovered in the early 1980s and named by Dr. Rose M. Johnstone later that decade, exosomes act as messengers, carrying signals between cells to support communication, repair, and regeneration.

Not all exosomes work the same way in skincare, though. Source matters:

• Platelet-derived exosomes – act as natural first responders, delivering peptides, antioxidants, and nucleic acids directly to areas of visible damage.
• Plant-derived exosomes – often marketed as "natural," but don't speak the same biological language as human skin.
• Animal-derived exosomes – closer to human biology than plants, but still not a precise match.
• Lab-derived exosomes – synthetic or cell-line versions that typically lack the complexity of exosomes from real human sources.

( plated )™ is built specifically around platelet-derived exosomes because they're recognized by skin as native signals, allowing them to trigger renewal rather than sit on the surface.

Why Skin (and Hair) Age in the First Place

Skin aging isn't just about time passing — it's about cumulative stress. UV exposure, pollution, hormones, and daily stress damage cells and break down collagen and elastin, eventually showing up as wrinkles, dark spots, and sagging. The same process happens on the scalp, appearing as thinning strands, breakage, and a rougher, less resilient look.

Traditional skincare tends to work on the surface — hydrating, exfoliating, brightening temporarily. Platelet-derived exosomes take a different approach: they tap into the skin's own repair signaling to support renewal from within, rather than just masking the surface.

The Science Behind ( plated )™

Each bottle is formulated with an extremely high concentration of exosomes — INTENSE Serum alone delivers over 1 trillion per bottle, and HAIR Serum contains more than 2 trillion. That concentration is extracted and stabilized through a proprietary process that preserves both potency and shelf stability, all sourced from FDA-regulated donation banks and purified under strict safety protocols.

Inside every exosome is a payload of active components that work in harmony with skin because they're human-native:

• Phosphoproteins – trigger renewal signaling on contact with skin.
• Peptides – help strengthen the skin barrier from within.
• Antioxidant enzymes – help defend against oxidative stress that drives dullness and fine lines.

The results are backed by real data, not just marketing claims. Across clinical studies, ( plated )™ has shown 94% of participants experiencing healthier-looking skin, 2x younger- and brighter-looking skin, and a 26% decrease in the appearance of wrinkles. For hair, 100% of participants saw improved scalp coverage, with a 3x increase in the appearance of hair density.

The ( plated )™ Lineup

INTENSE Serum — Our Most Advanced Exosome Serum

Built for multiple visible signs of aging at once, INTENSE Serum is the most concentrated formula in the line, delivering over 1 trillion platelet-derived exosomes per bottle. It's clinically proven to deliver 2x younger-looking skin, reduce the appearance of fine lines and wrinkles, fade the look of dark spots and uneven tone, and boost radiance — with benefits that continue building over time.

It's formulated with low-weight hyaluronic acid to support hydration alongside the exosomes, plus an antioxidant blend to help protect against free radical damage. It's suitable for all skin types, including sensitive skin, and is non-comedogenic. INTENSE Serum has picked up recognition including TIME Best Inventions 2024, multiple NewBeauty Awards, and Cosmopolitan's Holy Grail Beauty Award 2025. It's best suited for stressed or visibly aging skin, and pairs well with EYE Serum for a more complete routine.

DAILY Serum — Renewing Support for Youthful, Radiant Skin

Where INTENSE targets multiple aging concerns intensively, DAILY Serum is designed for daily, ongoing defense. It replenishes hydration while supporting continuous renewal, with visible results appearing in as little as 6 weeks and building over years of use.

It's formulated with glycerin to attract and lock in moisture, plus PAC6 to nourish and support a stronger skin barrier against environmental stress. Clinically, it's shown to reveal brighter, more luminous skin, smooth fine lines, fight redness and dark spots, and help defend against future signs of aging. It's especially well suited for sensitive or barrier-compromised skin and pairs naturally with EYE Serum.

EYE Serum — Advanced Renewal for Eyes

The eye area shows aging first, and EYE Serum is the first and only eye formula to harness platelet-derived exosomes specifically for this delicate zone. In as little as 4 weeks, it's clinically shown to improve the look of dark circles, crow's feet, crepey texture, and puffiness.

The formula combines exosomes with Coffee Arabica Extract to instantly de-puff and brighten tired eyes, and Dual Seaweed Extract to help fight sagging around the thin under-eye skin. Studies found 94% of users saw firmer-looking skin around the eyes, 89% saw less puffiness, and 78% saw fewer visible lines. It's safe for all skin types, including sensitive skin, and pairs well with either INTENSE or DAILY Serum for a fully renewed complexion.

HAIR Serum — Targeted Renewal for the Scalp and Hair

Nearly half of people experience thinning hair at some point, and HAIR Serum addresses it at the scalp level with more than 2 trillion platelet-derived exosomes per bottle. It's clinically proven to increase the appearance of thickness, fullness, and strength, improve density and scalp coverage, and help fight the look of shedding and breakage.

It's formulated with Curcuma Longa (Turmeric) Root Extract for its anti-inflammatory, antioxidant support, and Biotin to help reinforce follicle structure. In a double-blind, placebo-controlled study, 100% of participants showed improved scalp coverage, 96% reported better volume and fullness, and researchers recorded a 3x improvement in the appearance of hair density — with a lightweight, invisible-dry formula that fits easily into any routine.

Bring the Science Home